EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells.

Li, Jianhua; Lu, Erick; Yi, Tangsheng; Cyster, Jason G

Li, Jianhua; Lu, Erick; Yi, Tangsheng; Cyster, Jason G.

Affiliation

Li J; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California 94143, USA.
Lu E; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, California 94143, USA.
Yi T; Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Cyster JG; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California 94143, USA.

Nature ; 533(7601): 110-4, 2016 May 05.

Article in En | MEDLINE | ID: mdl-27147029

Subject(s)

Cell Differentiation; Dendritic Cells/immunology; Interleukin-2/immunology; Receptors, G-Protein-Coupled/metabolism; T-Lymphocytes, Helper-Inducer/cytology; T-Lymphocytes, Helper-Inducer/immunology; Animals; Cell Membrane/metabolism; Dendritic Cells/cytology; Female; Germinal Center/immunology; Hydroxycholesterols/metabolism; Inducible T-Cell Co-Stimulator Protein/metabolism; Interleukin-2 Receptor alpha Subunit/biosynthesis; Interleukin-2 Receptor alpha Subunit/chemistry; Interleukin-2 Receptor alpha Subunit/deficiency; Interleukin-2 Receptor alpha Subunit/metabolism; Lymphocyte Activation; Male; Mice; Plasma Cells/immunology; Receptors, G-Protein-Coupled/deficiency; Receptors, G-Protein-Coupled/genetics; Solubility

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Cell Differentiation / Interleukin-2 / T-Lymphocytes, Helper-Inducer / Receptors, G-Protein-Coupled Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nature Year: 2016 Type: Article Affiliation country: United States

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