Factor XI as a Therapeutic Target.

Gailani, David; Gruber, Andras

Gailani, David; Gruber, Andras.

Affiliation

Gailani D; From the Department of Pathology, Microbiology and Immunology and Department of Medicine, Vanderbilt University, Nashville, TN (D.G.); and Aronora, Inc, Portland, OR (A.G.). dave.gailani@vanderbilt.edu.
Gruber A; From the Department of Pathology, Microbiology and Immunology and Department of Medicine, Vanderbilt University, Nashville, TN (D.G.); and Aronora, Inc, Portland, OR (A.G.).

Arterioscler Thromb Vasc Biol ; 36(7): 1316-22, 2016 07.

Article in En | MEDLINE | ID: mdl-27174099

Subject(s)

Anticoagulants/therapeutic use; Blood Coagulation/drug effects; Factor XIa/antagonists & inhibitors; Fibrinolytic Agents/therapeutic use; Thrombosis/prevention & control; Animals; Anticoagulants/adverse effects; Disease Models, Animal; Drug Design; Factor XIa/metabolism; Fibrinolytic Agents/adverse effects; Hemorrhage/chemically induced; Humans; Molecular Targeted Therapy; Risk Factors; Thrombosis/blood; Treatment Outcome

Key words

factor XI; factor XII; hemorrhage; thrombin; thrombosis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Blood Coagulation / Factor XIa / Fibrinolytic Agents / Anticoagulants Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2016 Type: Article

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