Your browser doesn't support javascript.
loading
XPA: A key scaffold for human nucleotide excision repair.
Sugitani, Norie; Sivley, Robert M; Perry, Kelly E; Capra, John A; Chazin, Walter J.
Affiliation
  • Sugitani N; Departments of Biochemistry, Biological Sciences, Biomedical Informatics, Chemistry, and Computer Science, and Vanderbilt Genetics Institute and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232-7917, United States.
  • Sivley RM; Departments of Biochemistry, Biological Sciences, Biomedical Informatics, Chemistry, and Computer Science, and Vanderbilt Genetics Institute and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232-7917, United States.
  • Perry KE; Departments of Biochemistry, Biological Sciences, Biomedical Informatics, Chemistry, and Computer Science, and Vanderbilt Genetics Institute and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232-7917, United States.
  • Capra JA; Departments of Biochemistry, Biological Sciences, Biomedical Informatics, Chemistry, and Computer Science, and Vanderbilt Genetics Institute and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232-7917, United States.
  • Chazin WJ; Departments of Biochemistry, Biological Sciences, Biomedical Informatics, Chemistry, and Computer Science, and Vanderbilt Genetics Institute and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232-7917, United States. Electronic address: Walter.Chazin@vanderbilt.edu.
DNA Repair (Amst) ; 44: 123-135, 2016 08.
Article in En | MEDLINE | ID: mdl-27247238
ABSTRACT
Nucleotide excision repair (NER) is essential for removing many types of DNA lesions from the genome, yet the mechanisms of NER in humans remain poorly understood. This review summarizes our current understanding of the structure, biochemistry, interaction partners, mechanisms, and disease-associated mutations of one of the critical NER proteins, XPA.
Subject(s)
Key words
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xeroderma Pigmentosum / DNA / DNA Repair / Xeroderma Pigmentosum Group A Protein Limits: Animals / Humans Language: En Journal: DNA Repair (Amst) Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2016 Type: Article Affiliation country: United States
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xeroderma Pigmentosum / DNA / DNA Repair / Xeroderma Pigmentosum Group A Protein Limits: Animals / Humans Language: En Journal: DNA Repair (Amst) Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2016 Type: Article Affiliation country: United States