Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment.

Andersen, Anne Poder; Flinck, Mette; Oernbo, Eva Kjer; Pedersen, Nis Borbye; Viuff, Birgitte Martine; Pedersen, Stine Falsig

Andersen, Anne Poder; Flinck, Mette; Oernbo, Eva Kjer; Pedersen, Nis Borbye; Viuff, Birgitte Martine; Pedersen, Stine Falsig.

Affiliation

Andersen AP; Department of Biology, Section for Cell Biology and Physiology, Faculty of Science, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark.
Flinck M; Department of Biology, Section for Cell Biology and Physiology, Faculty of Science, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark.
Oernbo EK; Department of Biology, Section for Cell Biology and Physiology, Faculty of Science, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark.
Pedersen NB; Department of Biology, Section for Cell Biology and Physiology, Faculty of Science, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark.
Viuff BM; Department of Veterinary Disease Biology, Section for Molecular Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Strandboulevarden 49, DK-2100, Copenhagen, Denmark.
Pedersen SF; Department of Biology, Section for Cell Biology and Physiology, Faculty of Science, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark. sfpedersen@bio.ku.dk.

Mol Cancer ; 15(1): 45, 2016 06 06.

Article in En | MEDLINE | ID: mdl-27266704

Subject(s)

Breast Neoplasms/metabolism; Breast Neoplasms/pathology; Organic Anion Transporters/metabolism; Breast Neoplasms/genetics; Cell Line, Tumor; Cell Proliferation; Female; Gene Knockdown Techniques; Humans; Hydrogen-Ion Concentration; Hypoxia/metabolism; Monocarboxylic Acid Transporters/genetics; Monocarboxylic Acid Transporters/metabolism; Organic Anion Transporters/genetics; Sodium-Bicarbonate Symporters/genetics; Sodium-Bicarbonate Symporters/metabolism; Spheroids, Cellular; Tumor Cells, Cultured; Tumor Microenvironment

Key words

Acidbase transport; MCT1; MCT4; NBCn1; NHE1; Tumor microenvironment

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Organic Anion Transporters Limits: Female / Humans Language: En Journal: Mol Cancer Journal subject: NEOPLASIAS Year: 2016 Type: Article Affiliation country: Denmark

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