Relapsed diffuse large B-cell lymphoma present different genomic profiles between early and late relapses.

Broséus, Julien; Chen, Gaili; Hergalant, Sébastien; Ramstein, Gérard; Mounier, Nicolas; Guéant, Jean-Louis; Feugier, Pierre; Gisselbrecht, Christian; Thieblemont, Catherine; Houlgatte, Rémi

Broséus, Julien; Chen, Gaili; Hergalant, Sébastien; Ramstein, Gérard; Mounier, Nicolas; Guéant, Jean-Louis; Feugier, Pierre; Gisselbrecht, Christian; Thieblemont, Catherine; Houlgatte, Rémi.

Affiliation

Broséus J; Inserm U954, Faculty of Medicine, Nancy, France.
Chen G; Hematology, Laboratory Department, University Hospital of Nancy, Nancy, France.
Hergalant S; ZhongNan Hospital of Wuhan University, Wuhan, China.
Ramstein G; Inserm U954, Faculty of Medicine, Nancy, France.
Mounier N; LINA DUKe, UMR 6241, Université de Nantes, Nantes, France.
Guéant JL; Hemato-oncology, University Hospital of l'Archet, Nice, France.
Feugier P; Inserm U954, Faculty of Medicine, Nancy, France.
Gisselbrecht C; Biochemistry, Laboratory Department, University Hospital of Nancy, Nancy, France.
Thieblemont C; Inserm U954, Faculty of Medicine, Nancy, France.
Houlgatte R; Hematology Department, University Hospital of Nancy, Nancy, France.

Oncotarget ; 7(51): 83987-84002, 2016 Dec 20.

Article in En | MEDLINE | ID: mdl-27276707

Subject(s)

Biomarkers, Tumor/genetics; DNA Copy Number Variations; Gene Dosage; Gene Expression Profiling/methods; Lymphoma, Large B-Cell, Diffuse/genetics; Oligonucleotide Array Sequence Analysis; Transcriptome; Adult; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Lymphoma, Large B-Cell, Diffuse/drug therapy; Lymphoma, Large B-Cell, Diffuse/pathology; Male; Middle Aged; Phenotype; Predictive Value of Tests; Prospective Studies; Recurrence; Risk Factors; Time Factors; Treatment Failure; Young Adult

Key words

copy number variations; diffuse large B-cell lymphoma; early relapse; genomics; late relapse

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / Lymphoma, Large B-Cell, Diffuse / Gene Dosage / Oligonucleotide Array Sequence Analysis / Gene Expression Profiling / DNA Copy Number Variations / Transcriptome Type of study: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Oncotarget Year: 2016 Type: Article Affiliation country: France

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