Hibernation, Hypothermia and a Possible Therapeutic "Shifted Homeostasis" Induced by Central Activation of A1 Adenosine Receptor (A1AR).
Nihon Shinkei Seishin Yakurigaku Zasshi
; 36(2): 51-4, 2016 Apr.
Article
in En
| MEDLINE
| ID: mdl-27333659
ABSTRACT
The positive outcome that hypothermia contributes to brain and cardiac protection following ischemia has stimulated research in the development of pharmacological approaches to induce a hypothermic/hypometabolic state. Pharmacological manipulation of central autonomic thermoregulatory circuits could represent a potential target for the induction of a hypothermic state. Here we present a brief description of the CNS thermoregulatory centers and how the manipulation of these circuits can be useful in the treatment of pathological conditions such as stroke or brain hemorrhage.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Body Temperature Regulation
/
Receptor, Adenosine A1
/
Homeostasis
/
Hypothermia, Induced
Limits:
Animals
/
Humans
Language:
En
Journal:
Nihon Shinkei Seishin Yakurigaku Zasshi
Journal subject:
PSICOFARMACOLOGIA
Year:
2016
Type:
Article