TGFß-Responsive HMOX1 Expression Is Associated with Stemness and Invasion in Glioblastoma Multiforme.

Ghosh, Dhiman; Ulasov, Ilya V; Chen, LiPing; Harkins, Lualhati E; Wallenborg, Karolina; Hothi, Parvinder; Rostad, Steven; Hood, Leroy; Cobbs, Charles S

Ghosh, Dhiman; Ulasov, Ilya V; Chen, LiPing; Harkins, Lualhati E; Wallenborg, Karolina; Hothi, Parvinder; Rostad, Steven; Hood, Leroy; Cobbs, Charles S.

Affiliation

Ghosh D; The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Neuroscience Institute, Seattle. dhimankrishna.ghosh@swedish.org.
Ulasov IV; Institute for Systems Biology, Seattle. dhimankrishna.ghosh@swedish.org.
Chen L; The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Neuroscience Institute, Seattle.
Harkins LE; The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Neuroscience Institute, Seattle.
Wallenborg K; Department of Pathology and Laboratory Medicine, Birmingham Veterans Hospital, Birmingham.
Hothi P; Institute for Systems Biology, Seattle.
Rostad S; The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Neuroscience Institute, Seattle.
Hood L; The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Neuroscience Institute, Seattle.
Cobbs CS; CellNetix Pathology and Laboratories, Seattle.

Stem Cells ; 34(9): 2276-89, 2016 09.

Article in En | MEDLINE | ID: mdl-27354342

Subject(s)

Brain Neoplasms/pathology; Glioblastoma/pathology; Heme Oxygenase-1/metabolism; Neoplastic Stem Cells/metabolism; Neoplastic Stem Cells/pathology; Transforming Growth Factor beta/metabolism; Biomarkers, Tumor/metabolism; Brain Neoplasms/metabolism; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Glioblastoma/metabolism; Humans; Membrane Proteins/metabolism; Monocarboxylic Acid Transporters/metabolism; Neoplasm Invasiveness; Neural Stem Cells/metabolism; Prognosis; Spheroids, Cellular/metabolism; Symporters/metabolism

Key words

CSC; GBM; Invasion; NSC; Neurosphere; Pseudopalisading

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Brain Neoplasms / Transforming Growth Factor beta / Glioblastoma / Heme Oxygenase-1 Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Stem Cells Year: 2016 Type: Article

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