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Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias.
Wang, K; Sanchez-Martin, M; Wang, X; Knapp, K M; Koche, R; Vu, L; Nahas, M K; He, J; Hadler, M; Stein, E M; Tallman, M S; Donahue, A L; Frampton, G M; Lipson, D; Roels, S; Stephens, P J; Sanford, E M; Brennan, T; Otto, G A; Yelensky, R; Miller, V A; Kharas, M G; Levine, R L; Ferrando, A; Armstrong, S A; Krivtsov, A V.
Affiliation
  • Wang K; Foundation Medicine, Cambridge, MA, USA.
  • Sanchez-Martin M; Institute for Cancer Genetics Columbia University, New York, NY, USA.
  • Wang X; Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Knapp KM; Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Koche R; Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Vu L; Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Nahas MK; Foundation Medicine, Cambridge, MA, USA.
  • He J; Foundation Medicine, Cambridge, MA, USA.
  • Hadler M; Foundation Medicine, Cambridge, MA, USA.
  • Stein EM; Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Tallman MS; Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Donahue AL; Foundation Medicine, Cambridge, MA, USA.
  • Frampton GM; Foundation Medicine, Cambridge, MA, USA.
  • Lipson D; Foundation Medicine, Cambridge, MA, USA.
  • Roels S; Foundation Medicine, Cambridge, MA, USA.
  • Stephens PJ; Foundation Medicine, Cambridge, MA, USA.
  • Sanford EM; Foundation Medicine, Cambridge, MA, USA.
  • Brennan T; Foundation Medicine, Cambridge, MA, USA.
  • Otto GA; Foundation Medicine, Cambridge, MA, USA.
  • Yelensky R; Foundation Medicine, Cambridge, MA, USA.
  • Miller VA; Foundation Medicine, Cambridge, MA, USA.
  • Kharas MG; Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Levine RL; Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ferrando A; Institute for Cancer Genetics Columbia University, New York, NY, USA.
  • Armstrong SA; Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Krivtsov AV; Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Leukemia ; 31(1): 151-158, 2017 01.
Article in En | MEDLINE | ID: mdl-27363283
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia / Heterografts Type of study: Prognostic_studies Limits: Adolescent / Adult / Animals / Child / Humans / Middle aged Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2017 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia / Heterografts Type of study: Prognostic_studies Limits: Adolescent / Adult / Animals / Child / Humans / Middle aged Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2017 Type: Article Affiliation country: United States