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Preparation of Well-Defined DNA Samples for Reproducible Nanospectroscopic Measurements.
Lipiec, Ewelina; Japaridze, Aleksandre; Szczerbinski, Jacek; Dietler, Giovanni; Zenobi, Renato.
Affiliation
  • Lipiec E; Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland.
  • Japaridze A; The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, 31-342, Krakow, Poland.
  • Szczerbinski J; Laboratory of Physics of Living Matter, Ecole Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.
  • Dietler G; Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland.
  • Zenobi R; Laboratory of Physics of Living Matter, Ecole Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.
Small ; 12(35): 4821-4829, 2016 Sep.
Article in En | MEDLINE | ID: mdl-27434680
ABSTRACT
Due to its well-defined topology and chemical structure, DNA could become a biological standard sample in the field of nanospectroscopy. Tip-enhanced Raman spectroscopy (TERS) provides new insights into individual DNA molecules immobilized on flat mica crystals. The high sensitivity of TERS is used to assess the chemical changes that appear in DNA upon different surface immobilization protocols.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Nanostructures Language: En Journal: Small Journal subject: ENGENHARIA BIOMEDICA Year: 2016 Type: Article Affiliation country: Switzerland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Nanostructures Language: En Journal: Small Journal subject: ENGENHARIA BIOMEDICA Year: 2016 Type: Article Affiliation country: Switzerland