Molecular Diagnostic Testing for Aspergillus.
J Clin Microbiol
; 54(11): 2655-2660, 2016 11.
Article
in En
| MEDLINE
| ID: mdl-27487954
ABSTRACT
The direct detection of Aspergillus nucleic acid in clinical specimens has the potential to improve the diagnosis of aspergillosis by offering more rapid and sensitive identification of invasive infections than is possible with traditional techniques, such as culture or histopathology. Molecular tests for Aspergillus have been limited historically by lack of standardization and variable sensitivities and specificities. Recent efforts have been directed at addressing these limitations and optimizing assay performance using a variety of specimen types. This review provides a summary of standardization efforts and outlines the complexities of molecular testing for Aspergillus in clinical mycology.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Aspergillosis
/
Aspergillus
/
Molecular Diagnostic Techniques
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
J Clin Microbiol
Year:
2016
Type:
Article
Affiliation country:
United States