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Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing.
Didiot, Marie-Cécile; Hall, Lauren M; Coles, Andrew H; Haraszti, Reka A; Godinho, Bruno Mdc; Chase, Kathryn; Sapp, Ellen; Ly, Socheata; Alterman, Julia F; Hassler, Matthew R; Echeverria, Dimas; Raj, Lakshmi; Morrissey, David V; DiFiglia, Marian; Aronin, Neil; Khvorova, Anastasia.
Affiliation
  • Didiot MC; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Hall LM; Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Coles AH; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Haraszti RA; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Godinho BM; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Chase K; Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Sapp E; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Ly S; Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Alterman JF; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Hassler MR; Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Echeverria D; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Raj L; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Morrissey DV; Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
  • DiFiglia M; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Aronin N; Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
  • Khvorova A; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Mol Ther ; 24(10): 1836-1847, 2016 10.
Article in En | MEDLINE | ID: mdl-27506293

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Small Interfering / Exosomes / Huntingtin Protein / Neurons Limits: Animals / Humans Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2016 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Small Interfering / Exosomes / Huntingtin Protein / Neurons Limits: Animals / Humans Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2016 Type: Article Affiliation country: United States