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Transfusion Therapy in Children With Sickle Cell Disease.
Inati, Adlette; Mansour, Anthony G; Sabbouh, Toni; Amhez, Ghid; Hachem, Ahmad; Abbas, Hussein A.
Affiliation
  • Inati A; *Department of Pediatrics, Lebanese American University and University Medical Center Rizk Hospital, Beirut †School of Medicine, Lebanese American University, Byblos, Lebanon ‡Department of Molecular and Cellular Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX.
J Pediatr Hematol Oncol ; 39(2): 126-132, 2017 03.
Article in En | MEDLINE | ID: mdl-27509379
ABSTRACT
Hydroxyurea, blood transfusions, and hematopoietic stem cell transplantation represent the 3 disease-modifying therapies in children with sickle cell disease (SCD). Blood transfusions play an increasingly important role in both prevention and management of SCD complications in this age group. This review will focus on the indications of blood transfusion in children with SCD and modalities of its administration. It will also highlight the complications of this life-saving therapy and ways of optimizing transfusion to minimize its associated risks.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Transfusion / Anemia, Sickle Cell Type of study: Etiology_studies / Prognostic_studies Limits: Humans Language: En Journal: J Pediatr Hematol Oncol Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2017 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Transfusion / Anemia, Sickle Cell Type of study: Etiology_studies / Prognostic_studies Limits: Humans Language: En Journal: J Pediatr Hematol Oncol Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2017 Type: Article