Multiple unusual lung etiologies in a child with acute lymphocytic leukemia.
Pediatr Blood Cancer
; 64(3)2017 03.
Article
in En
| MEDLINE
| ID: mdl-27616461
ABSTRACT
Granulomatous lung disease is a rare and perplexing differential in pediatrics. Pulmonary Cryptococcus falls into the differential but is not high on the list, particularly in a non-AIDS patient. Methotrexate (MTX) is a commonly used agent for chemotherapy in oncology and has been documented to cause lung injury in both patients with rheumatologic and oncologic diseases. Our patient had chronic cough and then developed an opportunistic infection resulting in respiratory failure. Lung biopsy showed two underlying unusual diagnoses MTX lung injury and cryptococcal pneumonia. His case is presented with particular attention to his prolonged road to diagnosis.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pneumonia
/
Opportunistic Infections
/
Antineoplastic Combined Chemotherapy Protocols
/
Cryptococcosis
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
/
Lung Diseases
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
Limits:
Child
/
Humans
/
Male
Language:
En
Journal:
Pediatr Blood Cancer
Journal subject:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Year:
2017
Type:
Article