Ocular adnexal marginal zone lymphoma arising in a patient with IgG4-related ophthalmic disease.
Mod Rheumatol
; 29(2): 383-387, 2019 Mar.
Article
in En
| MEDLINE
| ID: mdl-27686866
A 41-year-old man was diagnosed with immunoglobulin G4-related disease (IgG4-RD) in both eyelids 4 years ago and exhibited good response to steroid therapy. However, rapid swelling of the right eyelid lesion was recently observed. As IgG4-RD progression was suspected, biopsy was performed. Although the histology was consistent with IgG4-RD, the infiltrating large atypical lymphoid cells showed immunoglobulin light-chain restriction and IgH gene rearrangement. Consequently, he was diagnosed with extranodal marginal zone lymphoma with abundant IgG4-positive cells.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Lymphoma, B-Cell, Marginal Zone
/
Eye Neoplasms
/
Eyelids
/
Immunoglobulin G4-Related Disease
/
Glucocorticoids
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
Mod Rheumatol
Year:
2019
Type:
Article
Affiliation country:
Japan