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Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells.
Hirashita, Yuka; Tsukamoto, Yoshiyuki; Yanagihara, Kazuyoshi; Fumoto, Shoichi; Hijiya, Naoki; Nakada, Chisato; Uchida, Tomohisa; Matsuura, Keiko; Kodama, Masaaki; Okimoto, Tadayoshi; Daa, Tsutomu; Seike, Masataka; Iha, Hidekatsu; Shirao, Kuniaki; Murakami, Kazunari; Moriyama, Masatsugu.
Affiliation
  • Hirashita Y; Department of Molecular Pathology, Faculty of Medicine, Oita University, Oita, Japan.
  • Tsukamoto Y; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita, Japan.
  • Yanagihara K; Department of Molecular Pathology, Faculty of Medicine, Oita University, Oita, Japan.
  • Fumoto S; Division of Biomarker Discovery, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba, Japan.
  • Hijiya N; Department of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita, Japan.
  • Nakada C; Department of Molecular Pathology, Faculty of Medicine, Oita University, Oita, Japan.
  • Uchida T; Department of Molecular Pathology, Faculty of Medicine, Oita University, Oita, Japan.
  • Matsuura K; Department of Molecular Pathology, Faculty of Medicine, Oita University, Oita, Japan.
  • Kodama M; Department of Biology, Faculty of Medicine, Oita University, Oita, Japan.
  • Okimoto T; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita, Japan.
  • Daa T; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita, Japan.
  • Seike M; Department of Diagnostic Pathology, Faculty of Medicine, Oita University, Oita, Japan.
  • Iha H; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita, Japan.
  • Shirao K; Department of Microbiology, Faculty of Medicine, Oita University, Oita, Japan.
  • Murakami K; Department of Medical Oncology and Hematology, Faculty of Medicine, Oita University, Oita, Japan.
  • Moriyama M; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita, Japan.
Cancer Sci ; 107(12): 1919-1928, 2016 Dec.
Article in En | MEDLINE | ID: mdl-27699948
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Ribosomal Protein S6 / Extracellular Signal-Regulated MAP Kinases / Protein Kinase Inhibitors Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Cancer Sci Year: 2016 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Ribosomal Protein S6 / Extracellular Signal-Regulated MAP Kinases / Protein Kinase Inhibitors Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Cancer Sci Year: 2016 Type: Article Affiliation country: Japan