IL-1ß is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.

Indalao, I L; Sawabuchi, T; Takahashi, E; Kido, H

Indalao, I L; Sawabuchi, T; Takahashi, E; Kido, H.

Affiliation

Indalao IL; Division of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima, 770-8503, Japan.
Sawabuchi T; Division of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima, 770-8503, Japan.
Takahashi E; Division of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima, 770-8503, Japan.
Kido H; Division of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima, 770-8503, Japan. kido@tokushima-u.ac.jp.

Arch Virol ; 162(1): 201-211, 2017 Jan.

Article in En | MEDLINE | ID: mdl-27714503

Subject(s)

Host-Pathogen Interactions; Interleukin-1beta/metabolism; Orthomyxoviridae Infections/pathology; Orthomyxoviridae/physiology; Trypsin/biosynthesis; Up-Regulation; Animals; Cell Line; Disease Models, Animal; Epithelial Cells/immunology; Epithelial Cells/virology; Female; Humans; Interleukin-6/metabolism; Lung/pathology; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Orthomyxoviridae / Trypsin / Up-Regulation / Orthomyxoviridae Infections / Interleukin-1beta / Host-Pathogen Interactions Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Arch Virol Year: 2017 Type: Article Affiliation country: Japan

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