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Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis.
Bartelink, Imke H; Lalmohamed, Arief; van Reij, Elisabeth M L; Dvorak, Christopher C; Savic, Rada M; Zwaveling, Juliette; Bredius, Robbert G M; Egberts, Antoine C G; Bierings, Marc; Kletzel, Morris; Shaw, Peter J; Nath, Christa E; Hempel, George; Ansari, Marc; Krajinovic, Maja; Théorêt, Yves; Duval, Michel; Keizer, Ron J; Bittencourt, Henrique; Hassan, Moustapha; Güngör, Tayfun; Wynn, Robert F; Veys, Paul; Cuvelier, Geoff D E; Marktel, Sarah; Chiesa, Robert; Cowan, Morton J; Slatter, Mary A; Stricherz, Melisa K; Jennissen, Cathryn; Long-Boyle, Janel R; Boelens, Jaap Jan.
Affiliation
  • Bartelink IH; Department of Medicine, University of California San Francisco, CA, USA.
  • Lalmohamed A; Clinical Pharmacy Department, University Medical Center Utrecht, Utrecht, Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, Netherlands.
  • van Reij EM; Clinical Pharmacy Department, University Medical Center Utrecht, Utrecht, Netherlands.
  • Dvorak CC; Pediatric Allergy, Immunology, and Bone Marrow Transplantation Division, University of California San Francisco, CA, USA.
  • Savic RM; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, CA, USA.
  • Zwaveling J; Leiden University Medical Center, Leiden, Netherlands.
  • Bredius RG; Leiden University Medical Center, Leiden, Netherlands.
  • Egberts AC; Clinical Pharmacy Department, University Medical Center Utrecht, Utrecht, Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, Netherlands.
  • Bierings M; Division of Pediatrics, Blood and Marrow Transplantation Program, University Medical Center Utrecht, Utrecht, Netherlands.
  • Kletzel M; Stem Cell Transplant Program, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA.
  • Shaw PJ; Division of Blood and Marrow Transplantation, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Nath CE; Division of Blood and Marrow Transplantation, The Children's Hospital at Westmead, Sydney, NSW, Australia.
  • Hempel G; Department of Clinical Pharmacy, Westfälische Wilhelms-Universität Münster, Institut für Pharmazeutische und Medizinische Chemie, Münster, Germany.
  • Ansari M; Département de l'Enfant et de l'Adolescent, Hôpital des Enfants, Geneva, Switzerland.
  • Krajinovic M; Charles-Bruneau Cancer Center, Department of Pediatrics, Faculty of Medicine, University of Montreal, Montreal, QC, Canada.
  • Théorêt Y; Department of Pharmacology, University of Montreal, Montreal, QC, Canada; Clinical Pharmacology Unit, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada.
  • Duval M; Charles-Bruneau Cancer Center, Department of Pediatrics, Faculty of Medicine, University of Montreal, Montreal, QC, Canada.
  • Keizer RJ; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, CA, USA; InsightRX, San Francisco, CA, USA.
  • Bittencourt H; Charles-Bruneau Cancer Center, Department of Pediatrics, Faculty of Medicine, University of Montreal, Montreal, QC, Canada.
  • Hassan M; Division of Experimental Cancer Medicine, Clinical Research Centre, Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Güngör T; Division of Stem Cell Transplantation and Children's Research Center, University Children's Hospital Zürich, Zürich, Switzerland.
  • Wynn RF; Department of Haematology and Bone Marrow Transplantation, The Royal Manchester Children's Hospital, Manchester, UK.
  • Veys P; Bone Marrow Transplantation Department, Great Ormond Street Hospital for Children, London, UK.
  • Cuvelier GD; CancerCare Manitoba, Winnipeg, MB, Canada.
  • Marktel S; Stem Cell Program, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Chiesa R; Bone Marrow Transplantation Department, Great Ormond Street Hospital for Children, London, UK; Stem Cell Program, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Cowan MJ; Pediatric Allergy, Immunology, and Bone Marrow Transplantation Division, University of California San Francisco, CA, USA.
  • Slatter MA; The Institute of Cellular Medicine, Newcastle University, Newcastle, UK.
  • Stricherz MK; Department of Hematopoietic Cell Transplant, Hematology, and Oncology, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA.
  • Jennissen C; Department of Hematopoietic Cell Transplant, Hematology, and Oncology, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA.
  • Long-Boyle JR; Department of Clinical Pharmacy, University of California San Francisco, CA, USA.
  • Boelens JJ; Division of Pediatrics, Blood and Marrow Transplantation Program, University Medical Center Utrecht, Utrecht, Netherlands; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands. Electronic address: j.j.boelens@umcutrecht.nl.
Lancet Haematol ; 3(11): e526-e536, 2016 Nov.
Article in En | MEDLINE | ID: mdl-27746112
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transplantation, Homologous / Busulfan / Hematopoietic Stem Cell Transplantation / Transplantation Conditioning / Area Under Curve / Dose-Response Relationship, Drug Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Lancet Haematol Year: 2016 Type: Article Affiliation country: United States
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transplantation, Homologous / Busulfan / Hematopoietic Stem Cell Transplantation / Transplantation Conditioning / Area Under Curve / Dose-Response Relationship, Drug Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Lancet Haematol Year: 2016 Type: Article Affiliation country: United States