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Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia.
Tasian, Sarah K; Teachey, David T; Li, Yong; Shen, Feng; Harvey, Richard C; Chen, I-Ming; Ryan, Theresa; Vincent, Tiffaney L; Willman, Cheryl L; Perl, Alexander E; Hunger, Stephen P; Loh, Mignon L; Carroll, Martin; Grupp, Stephan A.
Affiliation
  • Tasian SK; Division of Oncology, Department of Pediatrics, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Teachey DT; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Li Y; Division of Oncology, Department of Pediatrics, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Shen F; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Harvey RC; Division of Oncology, Department of Pediatrics, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Chen IM; Division of Oncology, Department of Pediatrics, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Ryan T; Department of Pathology, University of New Mexico, Albuquerque, NM.
  • Vincent TL; Department of Pathology, University of New Mexico, Albuquerque, NM.
  • Willman CL; Division of Oncology, Department of Pediatrics, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Perl AE; Division of Oncology, Department of Pediatrics, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Hunger SP; Department of Pathology, University of New Mexico, Albuquerque, NM.
  • Loh ML; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Carroll M; Division of Hematology, Department of Medicine, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA; and.
  • Grupp SA; Division of Oncology, Department of Pediatrics, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA.
Blood ; 129(2): 177-187, 2017 01 12.
Article in En | MEDLINE | ID: mdl-27777238
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Protein Kinase Inhibitors / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Antineoplastic Agents Type of study: Clinical_trials / Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2017 Type: Article Affiliation country: Panama
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Protein Kinase Inhibitors / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Antineoplastic Agents Type of study: Clinical_trials / Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2017 Type: Article Affiliation country: Panama