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In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis.
Kirschbaum, Klara; Sonner, Jana K; Zeller, Matthias W; Deumelandt, Katrin; Bode, Julia; Sharma, Rakesh; Krüwel, Thomas; Fischer, Manuel; Hoffmann, Angelika; Costa da Silva, Milene; Muckenthaler, Martina U; Wick, Wolfgang; Tews, Björn; Chen, John W; Heiland, Sabine; Bendszus, Martin; Platten, Michael; Breckwoldt, Michael O.
Affiliation
  • Kirschbaum K; German Cancer Consortium, Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Sonner JK; Department of Neuroradiology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
  • Zeller MW; German Cancer Consortium, Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Deumelandt K; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02115.
  • Bode J; Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02115.
  • Sharma R; German Cancer Consortium, Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Krüwel T; Schaller Research Group, University of Heidelberg and DKFZ, 69120 Heidelberg, Germany.
  • Fischer M; Molecular Mechanisms of Tumor Invasion, DKFZ, 69120 Heidelberg, Germany.
  • Hoffmann A; Schaller Research Group, University of Heidelberg and DKFZ, 69120 Heidelberg, Germany.
  • Costa da Silva M; Molecular Mechanisms of Tumor Invasion, DKFZ, 69120 Heidelberg, Germany.
  • Muckenthaler MU; Schaller Research Group, University of Heidelberg and DKFZ, 69120 Heidelberg, Germany.
  • Wick W; Molecular Mechanisms of Tumor Invasion, DKFZ, 69120 Heidelberg, Germany.
  • Tews B; Department of Neuroradiology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
  • Chen JW; Department of Neuroradiology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
  • Heiland S; Department of Pediatric Hematology, Oncology and Immunology, University of Heidelberg, 69120 Heidelberg, Germany.
  • Bendszus M; Molecular Medicine Partnership Unit, University Hospital Heidelberg, 69120 Heidelberg, Germany.
  • Platten M; Graduate Program in Areas of Basic and Applied Biology, Abel Salazar Biomedical Sciences Institute, University of Porto, 4050-313 Porto, Portugal.
  • Breckwoldt MO; Department of Pediatric Hematology, Oncology and Immunology, University of Heidelberg, 69120 Heidelberg, Germany.
Proc Natl Acad Sci U S A ; 113(46): 13227-13232, 2016 11 15.
Article in En | MEDLINE | ID: mdl-27799546

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Encephalomyelitis, Autoimmune, Experimental / Magnetite Nanoparticles / Multiple Sclerosis Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2016 Type: Article Affiliation country: Germany

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Encephalomyelitis, Autoimmune, Experimental / Magnetite Nanoparticles / Multiple Sclerosis Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2016 Type: Article Affiliation country: Germany