Erufosine increases RhoB expression in oral squamous carcinoma cells independent of its tumor suppressive mode of action - a short report.

Ansari, Shariq S; Akgün, Nurullah; Berger, Martin R

Ansari, Shariq S; Akgün, Nurullah; Berger, Martin R.

Affiliation

Ansari SS; Toxicology and Chemotherapy Unit, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.
Akgün N; Toxicology and Chemotherapy Unit, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.
Berger MR; Toxicology and Chemotherapy Unit, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany. m.berger@dkfz.de.

Cell Oncol (Dordr) ; 40(1): 89-96, 2017 Feb.

Article in En | MEDLINE | ID: mdl-27812856

Subject(s)

Antineoplastic Agents/pharmacology; Carcinoma, Squamous Cell/metabolism; Mouth Neoplasms/metabolism; Organophosphates/pharmacology; Quaternary Ammonium Compounds/pharmacology; rhoB GTP-Binding Protein/biosynthesis; Blotting, Western; Carcinoma, Squamous Cell/pathology; Cell Line, Tumor; Gene Knockdown Techniques; Humans; Mouth Neoplasms/pathology; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Up-Regulation

Key words

Akt signaling; Alkylphosphocholine; Apoptosis induction; Cell cycle analysis; Colony formation and migration assays; Head and neck cancer

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organophosphates / Mouth Neoplasms / Carcinoma, Squamous Cell / RhoB GTP-Binding Protein / Quaternary Ammonium Compounds / Antineoplastic Agents Limits: Humans Language: En Journal: Cell Oncol (Dordr) Year: 2017 Type: Article Affiliation country: Germany

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