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Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus.
Leslie, George J; Wang, Jianbin; Richardson, Max W; Haggarty, Beth S; Hua, Kevin L; Duong, Jennifer; Secreto, Anthony J; Jordon, Andrea P O; Romano, Josephine; Kumar, Kritika E; DeClercq, Joshua J; Gregory, Philip D; June, Carl H; Root, Michael J; Riley, James L; Holmes, Michael C; Hoxie, James A.
Affiliation
  • Leslie GJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
  • Wang J; Sangamo BioSciences Inc., Richmond, CA, United States of America.
  • Richardson MW; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
  • Haggarty BS; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
  • Hua KL; Sangamo BioSciences Inc., Richmond, CA, United States of America.
  • Duong J; Sangamo BioSciences Inc., Richmond, CA, United States of America.
  • Secreto AJ; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
  • Jordon AP; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
  • Romano J; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
  • Kumar KE; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
  • DeClercq JJ; Sangamo BioSciences Inc., Richmond, CA, United States of America.
  • Gregory PD; Sangamo BioSciences Inc., Richmond, CA, United States of America.
  • June CH; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
  • Root MJ; Department of Biochemistry and Molecular Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, United States of America.
  • Riley JL; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
  • Holmes MC; Sangamo BioSciences Inc., Richmond, CA, United States of America.
  • Hoxie JA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.
PLoS Pathog ; 12(11): e1005983, 2016 Nov.
Article in En | MEDLINE | ID: mdl-27855210
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / CD4-Positive T-Lymphocytes / HIV Envelope Protein gp41 / HIV Infections / HIV-1 / Receptors, CXCR4 / Virus Internalization Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2016 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / CD4-Positive T-Lymphocytes / HIV Envelope Protein gp41 / HIV Infections / HIV-1 / Receptors, CXCR4 / Virus Internalization Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2016 Type: Article Affiliation country: United States