BRCA1/2-negative hereditary triple-negative breast cancers exhibit BRCAness.

Domagala, Pawel; Hybiak, Jolanta; Cybulski, Cezary; Lubinski, Jan

Domagala, Pawel; Hybiak, Jolanta; Cybulski, Cezary; Lubinski, Jan.

Affiliation

Domagala P; Department of Pathology, Pomeranian Medical University, Szczecin, Poland.
Hybiak J; Department of Pathology, Pomeranian Medical University, Szczecin, Poland.
Cybulski C; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.
Lubinski J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.

Int J Cancer ; 140(7): 1545-1550, 2017 04 01.

Article in En | MEDLINE | ID: mdl-27943282

Subject(s)

Genes, BRCA1; Genes, BRCA2; Triple Negative Breast Neoplasms/genetics; Triple Negative Breast Neoplasms/metabolism; Adult; Aged; Aged, 80 and over; DNA Damage; DNA Repair; Female; Germ-Line Mutation; Homologous Recombination; Humans; Middle Aged; Phenotype; Poly(ADP-ribose) Polymerase Inhibitors/chemistry; Poly(ADP-ribose) Polymerases/metabolism; Real-Time Polymerase Chain Reaction; Registries; Surveys and Questionnaires; Young Adult

Key words

BRCA1/2; BRCAness; PARP inhibitors; breast cancer; triple-negative

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genes, BRCA1 / Genes, BRCA2 / Triple Negative Breast Neoplasms Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Middle aged Language: En Journal: Int J Cancer Year: 2017 Type: Article Affiliation country: Poland

Fulltext

XML

PubMed Links

Search on Google