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Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence.
Clarke, Starlynn C; Dumesic, Phillip A; Homer, Christina M; O'Donoghue, Anthony J; La Greca, Florencia; Pallova, Lenka; Majer, Pavel; Madhani, Hiten D; Craik, Charles S.
Affiliation
  • Clarke SC; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.
  • Dumesic PA; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America.
  • Homer CM; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America.
  • O'Donoghue AJ; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.
  • La Greca F; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.
  • Pallova L; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
  • Majer P; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
  • Madhani HD; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America.
  • Craik CS; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.
PLoS Pathog ; 12(12): e1006051, 2016 Dec.
Article in En | MEDLINE | ID: mdl-27977806
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fungal Proteins / Cryptococcosis / Cryptococcus neoformans / Aspartic Acid Proteases Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS Pathog Year: 2016 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fungal Proteins / Cryptococcosis / Cryptococcus neoformans / Aspartic Acid Proteases Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS Pathog Year: 2016 Type: Article Affiliation country: United States