Rat Aquaporin-5 Is pH-Gated Induced by Phosphorylation and Is Implicated in Oxidative Stress.

Rodrigues, Claudia; Mósca, Andreia Filipa; Martins, Ana Paula; Nobre, Tatiana; Prista, Catarina; Antunes, Fernando; Cipak Gasparovic, Ana; Soveral, Graça

Rodrigues, Claudia; Mósca, Andreia Filipa; Martins, Ana Paula; Nobre, Tatiana; Prista, Catarina; Antunes, Fernando; Cipak Gasparovic, Ana; Soveral, Graça.

Affiliation

Rodrigues C; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal. crodrigues@ff.ulisboa.pt.
Mósca AF; Department of Biochemistry and Human Biology, Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal. crodrigues@ff.ulisboa.pt.
Martins AP; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal. andreiafbm@ff.ulisboa.pt.
Nobre T; Department of Biochemistry and Human Biology, Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal. andreiafbm@ff.ulisboa.pt.
Prista C; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal. martinsap@ff.ulisboa.pt.
Antunes F; Department of Biochemistry and Human Biology, Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal. martinsap@ff.ulisboa.pt.
Cipak Gasparovic A; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal. t.nobre@campus.ul.pt.
Soveral G; Department of Biochemistry and Human Biology, Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal. t.nobre@campus.ul.pt.

Int J Mol Sci ; 17(12)2016 Dec 13.

Article in En | MEDLINE | ID: mdl-27983600

Subject(s)

Aquaporin 5/metabolism; Oxidative Stress; Animals; Aquaporin 5/chemistry; Cell Membrane Permeability/drug effects; Glucose/pharmacology; Humans; Hydrogen Peroxide/metabolism; Hydrogen Peroxide/toxicity; Hydrogen-Ion Concentration; Oxidation-Reduction/drug effects; Oxidative Stress/drug effects; Phosphorylation/drug effects; Protein Transport/drug effects; Rats; Saccharomyces cerevisiae/drug effects; Saccharomyces cerevisiae/metabolism; Subcellular Fractions/metabolism; Water/metabolism

Key words

aquaporin; hydrogen peroxide; oxidative stress; pH gating; permeability; phosphorylation; reactive oxygen species; yeast

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Aquaporin 5 Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2016 Type: Article Affiliation country: Portugal

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