Next-Generation Sequencing Reveals Pathway Activations and New Routes to Targeted Therapies in Cutaneous Metastatic Melanoma.

Carlson, J Andrew; Caldeira Xavier, Jose Candido; Tarasen, Ashley; Sheehan, Christine E; Otto, Geoff; Miller, Vincent A; Stephens, Philip J; Elvin, Julia A; Vergilio, Jo-Anne; Suh, James; Gay, Laurie M; Ross, Jeffrey S

Carlson, J Andrew; Caldeira Xavier, Jose Candido; Tarasen, Ashley; Sheehan, Christine E; Otto, Geoff; Miller, Vincent A; Stephens, Philip J; Elvin, Julia A; Vergilio, Jo-Anne; Suh, James; Gay, Laurie M; Ross, Jeffrey S.

Affiliation

Carlson JA; *Professor of Pathology and Dermatology, Albany Medical College, Albany, NY; Pathology Resident, Unversidade Estadual Paulista, Botucatu, Brazil; Pathology Resident, Albany Medical College, Albany, NY; §Director of Research, Associate Professor, Department of Pathology, Albany, Medical College, Albany, NY; ¶Research and Development, Foundation Medicine, Inc, Cambridge, MA; âChief Medical Officer, Foundation Medicine, Inc, Cambridge, MA; #Chief Scientific Officer, Foundation Medicine, Inc, Camb

Am J Dermatopathol ; 39(1): 1-13, 2017 Jan.

Article in En | MEDLINE | ID: mdl-28045747

Subject(s)

Biomarkers, Tumor/genetics; Gene Expression Profiling/methods; Genetic Variation; High-Throughput Nucleotide Sequencing; Melanoma/genetics; Skin Neoplasms/genetics; Adult; Aged; Aged, 80 and over; Antineoplastic Agents/therapeutic use; Computational Biology; Databases, Genetic; Drug Design; Female; Genetic Predisposition to Disease; Humans; Male; Melanoma/drug therapy; Melanoma/secondary; Middle Aged; Molecular Targeted Therapy; Neoplasm Staging; Phenotype; Precision Medicine; Predictive Value of Tests; Skin Neoplasms/drug therapy; Skin Neoplasms/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Genetic Variation / Biomarkers, Tumor / Gene Expression Profiling / High-Throughput Nucleotide Sequencing / Melanoma Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Am J Dermatopathol Year: 2017 Type: Article

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