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Adjuvant effects of a sequence-engineered mRNA vaccine: translational profiling demonstrates similar human and murine innate response.
Edwards, Darin K; Jasny, Edith; Yoon, Heesik; Horscroft, Nigel; Schanen, Brian; Geter, Tanya; Fotin-Mleczek, Mariola; Petsch, Benjamin; Wittman, Vaughan.
Affiliation
  • Edwards DK; Sanofi Pasteur, VaxDesign Campus, 2501 Discovery Drive Suite 300, Orlando, FL, USA. darin.edwards@sanofipasteur.com.
  • Jasny E; CureVac AG, Paul-Ehrlich-Str. 15, 72076, Tübingen, Germany.
  • Yoon H; Sanofi Pasteur, VaxDesign Campus, 2501 Discovery Drive Suite 300, Orlando, FL, USA.
  • Horscroft N; CureVac AG, Paul-Ehrlich-Str. 15, 72076, Tübingen, Germany.
  • Schanen B; Sanofi Pasteur, VaxDesign Campus, 2501 Discovery Drive Suite 300, Orlando, FL, USA.
  • Geter T; Sanofi Pasteur, VaxDesign Campus, 2501 Discovery Drive Suite 300, Orlando, FL, USA.
  • Fotin-Mleczek M; CureVac AG, Paul-Ehrlich-Str. 15, 72076, Tübingen, Germany.
  • Petsch B; CureVac AG, Paul-Ehrlich-Str. 15, 72076, Tübingen, Germany.
  • Wittman V; Sanofi Pasteur, VaxDesign Campus, 2501 Discovery Drive Suite 300, Orlando, FL, USA.
J Transl Med ; 15(1): 1, 2017 01 03.
Article in En | MEDLINE | ID: mdl-28049494
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Messenger / Influenza Vaccines / Genetic Engineering / Adjuvants, Immunologic / Translational Research, Biomedical / Immunity, Innate Limits: Animals / Humans Language: En Journal: J Transl Med Year: 2017 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Messenger / Influenza Vaccines / Genetic Engineering / Adjuvants, Immunologic / Translational Research, Biomedical / Immunity, Innate Limits: Animals / Humans Language: En Journal: J Transl Med Year: 2017 Type: Article Affiliation country: United States