Hepatitis E Virus (HEV) Infection in Anti-HEV Immunoglobulin G-Carrying Patients After Successful Hepatitis C Virus Treatment: Reactivation or Reinfection?

Rivero-Juarez, Antonio; Frias, Mario; Lopez-Lopez, Pedro; de Los Angeles Risalde, María; Brieva, Teresa; Machuca, Isabel; Camacho, Angela; Martinez-Peinado, Antonio; Gomez-Villamandos, Jose Carlos; Rivero, Antonio

Rivero-Juarez, Antonio; Frias, Mario; Lopez-Lopez, Pedro; de Los Angeles Risalde, María; Brieva, Teresa; Machuca, Isabel; Camacho, Angela; Martinez-Peinado, Antonio; Gomez-Villamandos, Jose Carlos; Rivero, Antonio.

Affiliation

Rivero-Juarez A; Unidad de Enfermedades Infecciosas and.
Frias M; Unidad de Enfermedades Infecciosas and.
Lopez-Lopez P; Unidad de Enfermedades Infecciosas and.
de Los Angeles Risalde M; Unidad de Enfermedades Infecciosas and.
Brieva T; Unidad de Enfermedades Infecciosas and.
Machuca I; Unidad de Enfermedades Infecciosas and.
Camacho A; Unidad de Enfermedades Infecciosas and.
Martinez-Peinado A; Servicio de Análisis Clínico, Hospital Universitario Reina Sofía de Córdoba, Instituto Maimonides de Investigación Biomédica de Córdoba, Universidad de Córdoba; and.
Gomez-Villamandos JC; Departamento de Sanidad Animal, Universidad de Córdoba, Spain.
Rivero A; Unidad de Enfermedades Infecciosas and.

Clin Infect Dis ; 64(7): 964-966, 2017 Apr 01.

Article in En | MEDLINE | ID: mdl-28077520

ABSTRACT

Although hepatitis E virus (HEV) is regarded as a self-limiting infection and anti-HEV antibodies seem to protect against reinfection, its pathogenesis is not well established. We describe 2 cases of acute symptomatic HEV infection after hepatitis C therapy in patients carrying anti-HEV immunoglobulin G antibodies, raising 2 major questions: reactivation or reinfection?

Subject(s)

Hepatitis Antibodies/immunology; Hepatitis E virus/immunology; Hepatitis E/immunology; Hepatitis E/virology; Immunoglobulin G/immunology; Aged; Antiretroviral Therapy, Highly Active; Antiviral Agents/therapeutic use; Coinfection; Female; HIV Infections/diagnosis; HIV Infections/drug therapy; HIV Infections/virology; Hepatitis Antibodies/blood; Hepatitis C/drug therapy; Hepatitis C/virology; Hepatitis E/diagnosis; Humans; Immunoglobulin G/blood; Immunoglobulin M/blood; Immunoglobulin M/immunology; Male; Middle Aged; Viral Load; Virus Activation

Key words

HIV; hepatitis C; hepatitis E; reactivation.; reinfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin G / Hepatitis Antibodies / Hepatitis E virus / Hepatitis E Type of study: Diagnostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2017 Type: Article

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