Rotating night shift work, sleep, and colorectal adenoma in women.
Int J Colorectal Dis
; 32(7): 1013-1018, 2017 Jul.
Article
in En
| MEDLINE
| ID: mdl-28097381
ABSTRACT
PURPOSE:
This study aims to investigate the associations of rotating night shift work history and sleep duration with risk of colorectal adenoma.METHODS:
We evaluated 56,275 cancer-free participants of the Nurses' Health Study II, who had their first colonoscopy or sigmoidoscopy between 1991 and 2011; rotating night shift work and sleep duration were reported by mailed questionnaire. Multivariable-adjusted logistic regression was used to estimate relative risks (RR) of colorectal adenoma, with 95% confidence intervals (CI), across categories of rotating night shift work history (none, 1-4, 5-9, and ≥10 years) and sleep duration (≤5, 6, 7, 8, and ≥9 h/day).RESULTS:
We found no association between duration of rotating night shift work and occurrence of colorectal adenoma (p-trend across shift work categories = 0.5). Women with the longest durations of rotating night shift work (≥10 years) had a similar risk of adenoma compared to women without a history of rotating night shift work (multivariable-adjusted RR = 0.96, 95% CI = 0.83-1.11). Similarly, there were no associations of shorter or longer sleep durations with adenoma risk (p-trend = 0.2 across sleep durations of ≤5 through 7 h/day and p-trend = 0.5 across sleep durations of 7 through ≥9 h/day). Results were similar when we examined associations according to adenoma location and subtype.CONCLUSIONS:
Our results do not support an association between rotating night shift work or sleep duration and risk of colorectal adenoma in women.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sleep
/
Colorectal Neoplasms
/
Adenoma
/
Shift Work Schedule
Type of study:
Etiology_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Int J Colorectal Dis
Journal subject:
GASTROENTEROLOGIA
Year:
2017
Type:
Article
Affiliation country:
United States