Trajectories of relapse in randomised, placebo-controlled trials of treatment discontinuation in major depressive disorder: an individual patient-level data meta-analysis.

Gueorguieva, Ralitza; Chekroud, Adam M; Krystal, John H

Gueorguieva, Ralitza; Chekroud, Adam M; Krystal, John H.

Affiliation

Gueorguieva R; Department of Biostatistics, School of Public Health, Yale University School of Medicine, New Haven, CT, USA. Electronic address: ralitza.gueorguieva@yale.edu.
Chekroud AM; Department of Psychology, Yale University, New Haven, CT, USA; Spring Health, New York City, NY, USA; Centre for Outcomes Research and Evaluation, Yale-New Haven Hospital, CT, USA.
Krystal JH; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; VA National Center for PTSD, VA Connecticut Healthcare System, West Haven, CT, USA.

Lancet Psychiatry ; 4(3): 230-237, 2017 Mar.

Article in En | MEDLINE | ID: mdl-28189575

Subject(s)

Depressive Disorder, Major/drug therapy; Patient Dropouts/statistics & numerical data; Withholding Treatment/statistics & numerical data; Adult; Antidepressive Agents/therapeutic use; Depressive Disorder, Major/epidemiology; Duloxetine Hydrochloride/administration & dosage; Duloxetine Hydrochloride/therapeutic use; Female; Fluoxetine/administration & dosage; Fluoxetine/therapeutic use; Humans; Male; Meta-Analysis as Topic; Middle Aged; Patient Dropouts/psychology; Placebo Effect; Protective Factors; Recurrence; Severity of Illness Index; Time Factors; Treatment Outcome; Withholding Treatment/trends

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Patient Dropouts / Withholding Treatment / Depressive Disorder, Major Type of study: Clinical_trials / Prognostic_studies / Systematic_reviews Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Lancet Psychiatry Year: 2017 Type: Article

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