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Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development.
Shi, Zhong-Dong; Lee, Kihyun; Yang, Dapeng; Amin, Sadaf; Verma, Nipun; Li, Qing V; Zhu, Zengrong; Soh, Chew-Li; Kumar, Ritu; Evans, Todd; Chen, Shuibing; Huangfu, Danwei.
Affiliation
  • Shi ZD; Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA.
  • Lee K; Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA; Weill Graduate School of Medical Sciences at Cornell University, 1300 York Avenue, New York, NY 10065, USA.
  • Yang D; Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA.
  • Amin S; Weill Graduate School of Medical Sciences at Cornell University, 1300 York Avenue, New York, NY 10065, USA.
  • Verma N; Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA; Tri-Institutional MD-PhD Program, Weill Graduate School of Medical Sciences at Cornell University, The Rockefeller University, Sloan Kettering Institute, 1300 York Avenue, New York, NY 10065, USA.
  • Li QV; Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Zhu Z; Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA.
  • Soh CL; Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA.
  • Kumar R; Department of Surgery, Weill Cornell Medical College, New York, NY 10065, USA.
  • Evans T; Department of Surgery, Weill Cornell Medical College, New York, NY 10065, USA.
  • Chen S; Department of Surgery, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address: shc2034@med.cornell.edu.
  • Huangfu D; Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA. Electronic address: huangfud@mskcc.org.
Cell Stem Cell ; 20(5): 675-688.e6, 2017 05 04.
Article in En | MEDLINE | ID: mdl-28196600
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pluripotent Stem Cells / GATA4 Transcription Factor / GATA6 Transcription Factor / Gene Editing Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cell Stem Cell Year: 2017 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pluripotent Stem Cells / GATA4 Transcription Factor / GATA6 Transcription Factor / Gene Editing Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cell Stem Cell Year: 2017 Type: Article Affiliation country: United States