Survival and Immunosuppression Induced by Hepatocyte Growth Factor in Chronic Lymphocytic Leukemia.

Giannoni, P; Cutrona, G; Totero, D de

Giannoni, P; Cutrona, G; Totero, D de.

Affiliation

Giannoni P; Stem Cell Laboratory, Department of Internal Medicine (DiMeS), University of Genoa, Via L.B. Alberti n.2, 16132 Genoa. Italy.
Cutrona G; Molecular Pathology Unit, IRCCS AOU San Martino-IST, Largo R. Benzi n.10, 16132 Genoa. Italy.
Totero D; Molecular Pathology Unit, IRCCS AOU San Martino-IST, Largo R. Benzi n.10, 16132 Genoa. Italy.

Curr Mol Med ; 17(1): 24-33, 2017.

Article in En | MEDLINE | ID: mdl-28231754

Subject(s)

Hepatocyte Growth Factor/metabolism; Leukemia, Lymphocytic, Chronic, B-Cell/etiology; Leukemia, Lymphocytic, Chronic, B-Cell/metabolism; Tumor Escape; Animals; B-Lymphocytes/immunology; B-Lymphocytes/metabolism; B-Lymphocytes/pathology; Gene Expression Regulation, Neoplastic/drug effects; Hepatocyte Growth Factor/genetics; Humans; Immunomodulation; Leukemia, Lymphocytic, Chronic, B-Cell/mortality; Leukemia, Lymphocytic, Chronic, B-Cell/pathology; Molecular Targeted Therapy; Prognosis; Protein Binding; Proto-Oncogene Proteins c-met/genetics; Proto-Oncogene Proteins c-met/metabolism; Signal Transduction/drug effects; Tumor Escape/genetics; Tumor Escape/immunology; Tumor Microenvironment/immunology

Key words

B-lymphoproliferative disorders; HGF; c-MET; immunosuppression; survival; therapeutical targets

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Hepatocyte Growth Factor / Tumor Escape Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Curr Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2017 Type: Article

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