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Combination of SDS-PAGE and intact mass analysis for rapid determination of heterogeneities in monoclonal antibody therapeutics.
Yamada, Hideaki; Matsumura, Chiemi; Yamada, Keita; Teshima, Koichiro; Hiroshima, Takashi; Kinoshita, Mitsuhiro; Suzuki, Shigeo; Kakehi, Kazuaki.
Affiliation
  • Yamada H; Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, Yodogawa-ku, Osaka, Japan.
  • Matsumura C; School of Pharmacy, Kindai University, Higashi-Osaka, Osaka, Japan.
  • Yamada K; School of Pharmacy, Kindai University, Higashi-Osaka, Osaka, Japan.
  • Teshima K; Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, Yodogawa-ku, Osaka, Japan.
  • Hiroshima T; Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, Yodogawa-ku, Osaka, Japan.
  • Kinoshita M; School of Pharmacy, Kindai University, Higashi-Osaka, Osaka, Japan.
  • Suzuki S; School of Pharmacy, Kindai University, Higashi-Osaka, Osaka, Japan.
  • Kakehi K; School of Pharmacy, Kindai University, Higashi-Osaka, Osaka, Japan.
Electrophoresis ; 38(9-10): 1344-1352, 2017 05.
Article in En | MEDLINE | ID: mdl-28261824
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides / Chromatography, High Pressure Liquid / Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Electrophoresis, Polyacrylamide Gel / Antibodies, Monoclonal Language: En Journal: Electrophoresis Year: 2017 Type: Article Affiliation country: Japan
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides / Chromatography, High Pressure Liquid / Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Electrophoresis, Polyacrylamide Gel / Antibodies, Monoclonal Language: En Journal: Electrophoresis Year: 2017 Type: Article Affiliation country: Japan