Evaluation of Adjusted and Unadjusted Indirect Comparison Methods in Benefit Assessment. A Simulation Study for Time-to-event Endpoints.

Kühnast, Sarah; Schiffner-Rohe, Julia; Rahnenführer, Jörg; Leverkus, Friedhelm

Kühnast, Sarah; Schiffner-Rohe, Julia; Rahnenführer, Jörg; Leverkus, Friedhelm.

Affiliation

Kühnast S; Sarah Kühnast, Pfizer Deutschland GmbH, Linkstr. 10, 10785 Berlin, Germany, E-Mail: sarah.kuehnast@pfizer.com.

Methods Inf Med ; 56(3): 261-267, 2017 May 18.

Article in En | MEDLINE | ID: mdl-28361159

Subject(s)

Biomarkers; Comparative Effectiveness Research/methods; Endpoint Determination/methods; Models, Statistical; Neoplasms/drug therapy; Neoplasms/epidemiology; Outcome Assessment, Health Care/methods; Antineoplastic Agents/therapeutic use; Bias; Computer Simulation; Germany/epidemiology; Humans; Neoplasms/diagnosis; Reproducibility of Results; Risk Assessment/methods; Sensitivity and Specificity

Key words

AMNOG; Bucher; Indirect comparisons; MAIC; dissimilarity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Models, Statistical / Outcome Assessment, Health Care / Endpoint Determination / Comparative Effectiveness Research / Neoplasms Type of study: Diagnostic_studies / Etiology_studies / Evaluation_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Country/Region as subject: Europa Language: En Journal: Methods Inf Med Year: 2017 Type: Article

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