Relationship among LRP1 expression, Pyk2 phosphorylation and MMP-9 activation in left ventricular remodelling after myocardial infarction.

Revuelta-López, Elena; Soler-Botija, Carol; Nasarre, Laura; Benitez-Amaro, Aleyda; de Gonzalo-Calvo, David; Bayes-Genis, Antoni; Llorente-Cortés, Vicenta

Revuelta-López, Elena; Soler-Botija, Carol; Nasarre, Laura; Benitez-Amaro, Aleyda; de Gonzalo-Calvo, David; Bayes-Genis, Antoni; Llorente-Cortés, Vicenta.

Affiliation

Revuelta-López E; Cardiovascular Research Center, CSIC-ICCC, IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Soler-Botija C; ICREC (Heart Failure and Cardiac Regeneration) Research Program, Health Sciences Research Institute Germans Tries i Pujol, Badalona (Barcelona), Spain.
Nasarre L; ICREC (Heart Failure and Cardiac Regeneration) Research Program, Health Sciences Research Institute Germans Tries i Pujol, Badalona (Barcelona), Spain.
Benitez-Amaro A; Cardiovascular Research Center, CSIC-ICCC, IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
de Gonzalo-Calvo D; Cardiovascular Research Center, CSIC-ICCC, IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Bayes-Genis A; Cardiovascular Research Center, CSIC-ICCC, IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Llorente-Cortés V; ICREC (Heart Failure and Cardiac Regeneration) Research Program, Health Sciences Research Institute Germans Tries i Pujol, Badalona (Barcelona), Spain.

J Cell Mol Med ; 21(9): 1915-1928, 2017 09.

Article in En | MEDLINE | ID: mdl-28378397

Subject(s)

Focal Adhesion Kinase 2/metabolism; Heart Ventricles/pathology; Matrix Metalloproteinase 9/metabolism; Myocardial Infarction/metabolism; Myocardial Infarction/pathology; Receptors, LDL/metabolism; Tumor Suppressor Proteins/metabolism; Ventricular Remodeling; Animals; Cell Hypoxia; Enzyme Activation; Fibroblasts/metabolism; Fibroblasts/pathology; Heart Ventricles/metabolism; Low Density Lipoprotein Receptor-Related Protein-1; Male; Matrix Metalloproteinase 2/metabolism; Mice, Inbred C57BL; Phosphorylation; RNA, Messenger/genetics; RNA, Messenger/metabolism; Receptors, LDL/genetics; Time Factors; Tumor Suppressor Proteins/genetics; Up-Regulation

Key words

LRP1; MMP-9; cardiac remodelling; myocardial infarction; pPyk2

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, LDL / Ventricular Remodeling / Matrix Metalloproteinase 9 / Tumor Suppressor Proteins / Focal Adhesion Kinase 2 / Heart Ventricles / Myocardial Infarction Limits: Animals Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2017 Type: Article Affiliation country: Spain

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