Gene Expression Signatures for Head and Neck Cancer Patient Stratification: Are Results Ready for Clinical Application?

Tonella, Luca; Giannoccaro, Marco; Alfieri, Salvatore; Canevari, Silvana; De Cecco, Loris

Tonella, Luca; Giannoccaro, Marco; Alfieri, Salvatore; Canevari, Silvana; De Cecco, Loris.

Affiliation

Tonella L; Functional Genomics and Bioinformatics, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133, Milan, Italy.
Giannoccaro M; Functional Genomics and Bioinformatics, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133, Milan, Italy.
Alfieri S; Head and Neck Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Canevari S; Functional Genomics and Bioinformatics, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133, Milan, Italy. silvana.canevari@istitutotumori.mi.it.
De Cecco L; Functional Genomics and Bioinformatics, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, via Amadeo 42, 20133, Milan, Italy. loris.dececco@istitutotumori.mi.it.

Curr Treat Options Oncol ; 18(5): 32, 2017 05.

Article in En | MEDLINE | ID: mdl-28474265

Subject(s)

Biomarkers, Tumor; Gene Expression Profiling; Head and Neck Neoplasms/diagnosis; Head and Neck Neoplasms/genetics; Transcriptome; Cell Transformation, Neoplastic/genetics; Cell Transformation, Viral; Gene Expression Regulation, Neoplastic; Genomics/methods; Head and Neck Neoplasms/mortality; Head and Neck Neoplasms/therapy; Humans; Meta-Analysis as Topic; Neoplasm Metastasis; Neoplasm Recurrence, Local; Patient Outcome Assessment; Prognosis

Key words

Gene expression; HNSCC; Meta-analysis-subtype stratification; Microarray; RNA-seq; Therapy prediction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / Gene Expression Profiling / Transcriptome / Head and Neck Neoplasms Type of study: Prognostic_studies / Systematic_reviews Limits: Humans Language: En Journal: Curr Treat Options Oncol Journal subject: NEOPLASIAS Year: 2017 Type: Article Affiliation country: Italy

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