Kinetic modeling predicts a stimulatory role for ribosome collisions at elongation stall sites in bacteria.

Ferrin, Michael A; Subramaniam, Arvind R

Ferrin, Michael A; Subramaniam, Arvind R.

Affiliation

Ferrin MA; Basic Sciences Division and Computational Biology Program of Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, United States.
Subramaniam AR; Basic Sciences Division and Computational Biology Program of Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, United States.

Elife ; 62017 05 12.

Article in En | MEDLINE | ID: mdl-28498106

Subject(s)

Escherichia coli/metabolism; Protein Biosynthesis; Ribosomes/metabolism; Computer Simulation; Kinetics

Key words

E. coli; amino acid starvation; computational biology; kinetic modeling; premature termination; quality control; ribosome collisions; ribosome stalling; systems biology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribosomes / Protein Biosynthesis / Escherichia coli Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Elife Year: 2017 Type: Article Affiliation country: United States

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