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Reprogramming progeria fibroblasts re-establishes a normal epigenetic landscape.
Chen, Zhaoyi; Chang, Wing Y; Etheridge, Alton; Strickfaden, Hilmar; Jin, Zhigang; Palidwor, Gareth; Cho, Ji-Hoon; Wang, Kai; Kwon, Sarah Y; Doré, Carole; Raymond, Angela; Hotta, Akitsu; Ellis, James; Kandel, Rita A; Dilworth, F Jeffrey; Perkins, Theodore J; Hendzel, Michael J; Galas, David J; Stanford, William L.
Affiliation
  • Chen Z; The Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, K1H 8L6.
  • Chang WY; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada.
  • Etheridge A; The Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, K1H 8L6.
  • Strickfaden H; Pacific Northwest Diabetes Research Institute, 720 Broadway, Seattle, WA, 98103, USA.
  • Jin Z; Cross Cancer Institute and the Department of Experimental Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada, T6G 1Z2.
  • Palidwor G; Cross Cancer Institute and the Department of Experimental Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada, T6G 1Z2.
  • Cho JH; The Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, K1H 8L6.
  • Wang K; Ottawa Bioinformatics Core Facility, The Sprott Centre for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, K1H 8L6.
  • Kwon SY; Pacific Northwest Diabetes Research Institute, 720 Broadway, Seattle, WA, 98103, USA.
  • Doré C; Pacific Northwest Diabetes Research Institute, 720 Broadway, Seattle, WA, 98103, USA.
  • Raymond A; The Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, K1H 8L6.
  • Hotta A; Department of Chemical Engineering, University of Toronto, Toronto, Ontario, Canada.
  • Ellis J; The Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, K1H 8L6.
  • Kandel RA; The Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, K1H 8L6.
  • Dilworth FJ; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
  • Perkins TJ; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Hendzel MJ; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
  • Galas DJ; Pathology and Experimental Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada.
  • Stanford WL; The Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, K1H 8L6.
Aging Cell ; 16(4): 870-887, 2017 08.
Article in En | MEDLINE | ID: mdl-28597562
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Progeria / Lamin Type A / Epigenesis, Genetic / Cellular Reprogramming / Induced Pluripotent Stem Cells / Fibroblasts Type of study: Observational_studies Limits: Humans Language: En Journal: Aging Cell Year: 2017 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Progeria / Lamin Type A / Epigenesis, Genetic / Cellular Reprogramming / Induced Pluripotent Stem Cells / Fibroblasts Type of study: Observational_studies Limits: Humans Language: En Journal: Aging Cell Year: 2017 Type: Article