T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways.

Hosokawa, Kohei; Kajigaya, Sachiko; Keyvanfar, Keyvan; Qiao, Wangmin; Xie, Yanling; Townsley, Danielle M; Feng, Xingmin; Young, Neal S

Hosokawa, Kohei; Kajigaya, Sachiko; Keyvanfar, Keyvan; Qiao, Wangmin; Xie, Yanling; Townsley, Danielle M; Feng, Xingmin; Young, Neal S.

Affiliation

Hosokawa K; Cell Biology Section, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892; and kohei.hosokawa@nih.gov.
Kajigaya S; Cell Biology Section, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892; and.
Keyvanfar K; Cell Biology Section, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892; and.
Qiao W; Beijing Genomics Institute-Shenzhen, Shenzhen 518083, China.
Xie Y; Beijing Genomics Institute-Shenzhen, Shenzhen 518083, China.
Townsley DM; Cell Biology Section, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892; and.
Feng X; Cell Biology Section, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892; and.
Young NS; Cell Biology Section, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892; and.

J Immunol ; 199(2): 477-488, 2017 07 15.

Article in En | MEDLINE | ID: mdl-28630090

Subject(s)

Hemoglobinuria, Paroxysmal/immunology; Metabolic Networks and Pathways/genetics; T-Lymphocyte Subsets/immunology; Transcriptome; Activating Transcription Factor 2/genetics; Activating Transcription Factor 2/metabolism; Adult; CD30 Ligand/genetics; CD30 Ligand/metabolism; CD4-Positive T-Lymphocytes/immunology; Female; Gene Expression Profiling; Gene Expression Regulation/immunology; Hemoglobinuria, Paroxysmal/metabolism; Hemoglobinuria, Paroxysmal/physiopathology; Humans; Insulin-Like Growth Factor I/genetics; Insulin-Like Growth Factor I/metabolism; Male; Methyltransferases/genetics; Methyltransferases/metabolism; Middle Aged; Real-Time Polymerase Chain Reaction; Sequence Analysis, RNA; Signal Transduction/genetics; T-Lymphocyte Subsets/metabolism; Tumor Necrosis Factor alpha-Induced Protein 3/genetics; Tumor Necrosis Factor alpha-Induced Protein 3/metabolism; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocyte Subsets / Metabolic Networks and Pathways / Transcriptome / Hemoglobinuria, Paroxysmal Type of study: Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Immunol Year: 2017 Type: Article

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