Caerulomycin A suppresses the differentiation of naïve T cells and alleviates the symptoms of experimental autoimmune encephalomyelitis.

Kujur, Weshely; Gurram, Rama Krishna; Maurya, Sudeep K; Nadeem, Sajid; Chodisetti, Sathi Babu; Khan, Nargis; Agrewala, Javed Naim

Kujur, Weshely; Gurram, Rama Krishna; Maurya, Sudeep K; Nadeem, Sajid; Chodisetti, Sathi Babu; Khan, Nargis; Agrewala, Javed Naim.

Affiliation

Kujur W; a Immunology Laboratory , CSIR-Institute of Microbial Technology , Chandigarh , India.
Gurram RK; a Immunology Laboratory , CSIR-Institute of Microbial Technology , Chandigarh , India.
Maurya SK; b National Institute of Allergy and Infectious Diseases , Bethesda , MD , USA.
Nadeem S; a Immunology Laboratory , CSIR-Institute of Microbial Technology , Chandigarh , India.
Chodisetti SB; a Immunology Laboratory , CSIR-Institute of Microbial Technology , Chandigarh , India.
Khan N; a Immunology Laboratory , CSIR-Institute of Microbial Technology , Chandigarh , India.
Agrewala JN; c Department of Microbiology and Immunology , Pennsylvania State University College of Medicine , Hershey , PA , USA.

Autoimmunity ; 50(5): 317-328, 2017 Aug.

Article in En | MEDLINE | ID: mdl-28686480

Subject(s)

Cell Differentiation/drug effects; Cell Differentiation/immunology; Encephalomyelitis, Autoimmune, Experimental/diagnosis; Encephalomyelitis, Autoimmune, Experimental/immunology; Immunosuppressive Agents/pharmacology; Pyridines/pharmacology; T-Lymphocytes/drug effects; T-Lymphocytes/immunology; Animals; Biomarkers; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental/drug therapy; Female; Immunologic Memory; Immunophenotyping; Mice; Multiple Sclerosis/diagnosis; Multiple Sclerosis/drug therapy; Multiple Sclerosis/immunology; Phenotype; T-Lymphocyte Subsets; T-Lymphocytes/cytology; T-Lymphocytes/metabolism

Key words

CaeA; EAE; Immunosuppression; Th1 cells; Th17; Tregs

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / T-Lymphocytes / Cell Differentiation / Encephalomyelitis, Autoimmune, Experimental / Immunosuppressive Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Autoimmunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2017 Type: Article Affiliation country: India

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