Body Temperature Cycles Control Rhythmic Alternative Splicing in Mammals.

Preußner, Marco; Goldammer, Gesine; Neumann, Alexander; Haltenhof, Tom; Rautenstrauch, Pia; Müller-McNicoll, Michaela; Heyd, Florian

Preußner, Marco; Goldammer, Gesine; Neumann, Alexander; Haltenhof, Tom; Rautenstrauch, Pia; Müller-McNicoll, Michaela; Heyd, Florian.

Affiliation

Preußner M; Laboratory of RNA Biochemistry, Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 6, 14195 Berlin, Germany. Electronic address: mpreussner@zedat.fu-berlin.de.
Goldammer G; Laboratory of RNA Biochemistry, Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 6, 14195 Berlin, Germany.
Neumann A; Laboratory of RNA Biochemistry, Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 6, 14195 Berlin, Germany.
Haltenhof T; Laboratory of RNA Biochemistry, Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 6, 14195 Berlin, Germany.
Rautenstrauch P; Laboratory of RNA Biochemistry, Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 6, 14195 Berlin, Germany.
Müller-McNicoll M; Goethe University Frankfurt, Institute for Cell Biology and Neuroscience, Max-von-Laue-Strasse 13, 60438 Frankfurt am Main, Germany.
Heyd F; Laboratory of RNA Biochemistry, Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 6, 14195 Berlin, Germany. Electronic address: florian.heyd@fu-berlin.de.

Mol Cell ; 67(3): 433-446.e4, 2017 Aug 03.

Article in En | MEDLINE | ID: mdl-28689656

Subject(s)

Alternative Splicing; Body Temperature Regulation; Circadian Clocks; Circadian Rhythm; TATA-Box Binding Protein/metabolism; 5' Untranslated Regions; Animals; Cell Line, Tumor; Exons; Female; HEK293 Cells; Humans; Male; Mice; Mice, Inbred C57BL; NIH 3T3 Cells; Phosphorylation; RNA Interference; Serine-Arginine Splicing Factors/genetics; Serine-Arginine Splicing Factors/metabolism; Splicing Factor U2AF/genetics; Splicing Factor U2AF/metabolism; TATA-Box Binding Protein/genetics; Time Factors; Transfection

Key words

SR proteins; Tbp; U2af; alternative splicing; body temperature; circadian clock; molecular thermometer; phosphorylation; splicing network

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Body Temperature Regulation / Circadian Rhythm / Alternative Splicing / TATA-Box Binding Protein / Circadian Clocks Limits: Animals / Female / Humans / Male Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2017 Type: Article

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