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Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Metelev, Mikhail; Osterman, Ilya A; Ghilarov, Dmitry; Khabibullina, Nelli F; Yakimov, Alexander; Shabalin, Konstantin; Utkina, Irina; Travin, Dmitry Y; Komarova, Ekaterina S; Serebryakova, Marina; Artamonova, Tatyana; Khodorkovskii, Mikhail; Konevega, Andrey L; Sergiev, Petr V; Severinov, Konstantin; Polikanov, Yury S.
Affiliation
  • Metelev M; Research Center of Nanobiotechnologies, Peter the Great St.Petersburg Polytechnic University, St. Petersburg, Russia.
  • Osterman IA; Institute of Antimicrobial Chemotherapy, Smolensk State Medical Academy, Smolensk, Russia.
  • Ghilarov D; Center for Data-Intensive Biomedicine and Biotechnology, Skolkovo Institute of Science and Technology, Moscow, Russia.
  • Khabibullina NF; Institute of Gene Biology of the Russian Academy of Sciences, Moscow, Russia.
  • Yakimov A; Center for Data-Intensive Biomedicine and Biotechnology, Skolkovo Institute of Science and Technology, Moscow, Russia.
  • Shabalin K; Department of Chemistry and A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
  • Utkina I; Center for Data-Intensive Biomedicine and Biotechnology, Skolkovo Institute of Science and Technology, Moscow, Russia.
  • Travin DY; Institute of Gene Biology of the Russian Academy of Sciences, Moscow, Russia.
  • Komarova ES; Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Serebryakova M; Research Center of Nanobiotechnologies, Peter the Great St.Petersburg Polytechnic University, St. Petersburg, Russia.
  • Artamonova T; Petersburg Nuclear Physics Institute, NRC Kurchatov Institute, Gatchina, Russia.
  • Khodorkovskii M; Petersburg Nuclear Physics Institute, NRC Kurchatov Institute, Gatchina, Russia.
  • Konevega AL; Research Center of Nanobiotechnologies, Peter the Great St.Petersburg Polytechnic University, St. Petersburg, Russia.
  • Sergiev PV; Center for Data-Intensive Biomedicine and Biotechnology, Skolkovo Institute of Science and Technology, Moscow, Russia.
  • Severinov K; Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.
  • Polikanov YS; Center for Data-Intensive Biomedicine and Biotechnology, Skolkovo Institute of Science and Technology, Moscow, Russia.
Nat Chem Biol ; 13(10): 1129-1136, 2017 Oct.
Article in En | MEDLINE | ID: mdl-28846667
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Ribosomes / Klebsiella pneumoniae / Anti-Bacterial Agents Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2017 Type: Article Affiliation country: RUSSIA
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Ribosomes / Klebsiella pneumoniae / Anti-Bacterial Agents Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2017 Type: Article Affiliation country: RUSSIA