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Design, synthesis, and SAR study of 3-(benzo[d][1,3]dioxol-5-yl)-N-benzylpropanamide as novel potent synergists against fluconazole-resistant Candida albicans.
Cai, Zhan; Ding, Zichao; Hao, Yumeng; Ni, Tingjunhong; Xie, Fei; Zhao, Jing; Li, Ran; Yu, Shichong; Wang, Ting; Chai, Xiaoyun; Jin, Yongsheng; Gao, Yue; Zhang, Dazhi; Jiang, Yuanying.
Affiliation
  • Cai Z; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.
  • Ding Z; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.
  • Hao Y; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China; School of Pharmacy, Fujian University of Traditional Chinese Medicine, 1 Qiuyang Road, Fuzhou 350112, China.
  • Ni T; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.
  • Xie F; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.
  • Zhao J; School of Pharmacy, Fujian University of Traditional Chinese Medicine, 1 Qiuyang Road, Fuzhou 350112, China.
  • Li R; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.
  • Yu S; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.
  • Wang T; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.
  • Chai X; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.
  • Jin Y; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.
  • Gao Y; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.
  • Zhang D; Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China; School of Pharmacy, Fujian University of Traditional Chinese Medicine, 1 Qiuyang Road, Fuzhou 350112, China. Electronic address: zdzhang_yjhx@smmu.edu.cn.
  • Jiang Y; Center of New Drug Research, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China. Electronic address: jiangyy@smmu.edu.cn.
Bioorg Med Chem Lett ; 27(19): 4571-4575, 2017 10 01.
Article in En | MEDLINE | ID: mdl-28874321
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida albicans / Drug Design / Fluconazole / Benzodioxoles / Antifungal Agents Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida albicans / Drug Design / Fluconazole / Benzodioxoles / Antifungal Agents Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Type: Article Affiliation country: China