A frameshift mutation in BRCA1 leads to hereditary breast and ovarian cancer in one part of a family and to familial pancreatic cancer in another.

Gieldon, Laura; Wagner, Johannes; Rump, Andreas

Gieldon, Laura; Wagner, Johannes; Rump, Andreas.

Affiliation

Gieldon L; Core Unit for Molecular Tumordiagnostics (CMTD), National Center for Tumor Diseases (NCT) partner site, Dresden, Germany. Laura.Gieldon@tu-dresden.de.
Wagner J; German Cancer Research Center (DKFZ), Heidelberg, Germany. Laura.Gieldon@tu-dresden.de.
Rump A; German Cancer Consortium (DKTK), Dresden, Germany. Laura.Gieldon@tu-dresden.de.

Breast Cancer Res Treat ; 167(1): 305-307, 2018 01.

Article in En | MEDLINE | ID: mdl-28900739

Subject(s)

BRCA1 Protein/genetics; Breast Neoplasms/genetics; Ovarian Neoplasms/genetics; Pancreatic Neoplasms/genetics; Adult; Aged; Breast Neoplasms/epidemiology; Breast Neoplasms/pathology; Female; Frameshift Mutation/genetics; Genetic Predisposition to Disease; Humans; Loss of Heterozygosity/genetics; Middle Aged; Ovarian Neoplasms/epidemiology; Ovarian Neoplasms/pathology; Pancreatic Neoplasms/epidemiology; Pancreatic Neoplasms/pathology; Pedigree

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Pancreatic Neoplasms / Breast Neoplasms / BRCA1 Protein Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Breast Cancer Res Treat Year: 2018 Type: Article Affiliation country: Germany

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