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Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aß-induced mitochondrial dysfunction.
Park, Insun; Londhe, Ashwini M; Lim, Ji Woong; Park, Beoung-Geon; Jung, Seo Yun; Lee, Jae Yeol; Lim, Sang Min; No, Kyoung Tai; Lee, Jiyoun; Pae, Ae Nim.
Affiliation
  • Park I; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.
  • Londhe AM; Department of Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
  • Lim JW; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.
  • Park BG; Division of Bio-Medical Science and Technology, KIST School, Korea University of Science and Technology, Seoul, 02792, Republic of Korea.
  • Jung SY; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.
  • Lee JY; Department of Converging Science and Technology, KyungHee University, Seoul, 02447, Republic of Korea.
  • Lim SM; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.
  • No KT; Center for Neuro-Medicine, Korea Institute of Science and Technology (KIST), Hwarangno 14- gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.
  • Lee J; School of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea.
  • Pae AN; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.
J Comput Aided Mol Des ; 31(10): 929-941, 2017 Oct.
Article in En | MEDLINE | ID: mdl-28913661
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclosporine / Neuroprotective Agents / Cyclophilins / Mitochondria Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Comput Aided Mol Des Journal subject: BIOLOGIA MOLECULAR / ENGENHARIA BIOMEDICA Year: 2017 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclosporine / Neuroprotective Agents / Cyclophilins / Mitochondria Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Comput Aided Mol Des Journal subject: BIOLOGIA MOLECULAR / ENGENHARIA BIOMEDICA Year: 2017 Type: Article