Evaluation of the cytotoxicity of the Bithionol-paclitaxel combination in a panel of human ovarian cancer cell lines.

Ayyagari, Vijayalakshmi N; Diaz-Sylvester, Paula L; Hsieh, Tsung-Han Jeff; Brard, Laurent

Ayyagari, Vijayalakshmi N; Diaz-Sylvester, Paula L; Hsieh, Tsung-Han Jeff; Brard, Laurent.

Affiliation

Ayyagari VN; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL, United States of America.
Diaz-Sylvester PL; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL, United States of America.
Hsieh TJ; Center for Clinical Research, Southern Illinois University School of Medicine, Springfield, IL, United States of America.
Brard L; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL, United States of America.

PLoS One ; 12(9): e0185111, 2017.

Article in En | MEDLINE | ID: mdl-28931042

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/pharmacology; Ovarian Neoplasms/drug therapy; Apoptosis/drug effects; Bithionol/administration & dosage; Cell Cycle/drug effects; Cell Cycle/physiology; Cell Line, Tumor; Cisplatin/pharmacology; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm/drug effects; Drug Screening Assays, Antitumor; Female; Humans; Inhibitory Concentration 50; Ovarian Neoplasms/metabolism; Ovarian Neoplasms/pathology; Paclitaxel/administration & dosage; Phosphoric Diester Hydrolases/metabolism; Reactive Oxygen Species/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Antineoplastic Combined Chemotherapy Protocols Limits: Female / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2017 Type: Article Affiliation country: United States

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