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Ruxolitinib is effective and safe in Japanese patients with hydroxyurea-resistant or hydroxyurea-intolerant polycythemia vera with splenomegaly.
Kirito, Keita; Suzuki, Kenshi; Miyamura, Koichi; Takeuchi, Masahiro; Handa, Hiroshi; Okamoto, Shinichiro; Gadbaw, Brian; Yamauchi, Kyosuke; Amagasaki, Taro; Ito, Kazuo; Hino, Masayuki.
Affiliation
  • Kirito K; Department of Hematology and Oncology, University of Yamanashi, 1110 Simokawakita, Chuou-shi, Yamanashi, 409-3898, Japan. kirito@yamanashi.ac.jp.
  • Suzuki K; Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan.
  • Miyamura K; Department of Hematology, Nagoya Daiichi Hospital, Nagoya, Japan.
  • Takeuchi M; Department of Hematology, Chiba University Hospital, Chiba, Japan.
  • Handa H; Department of Medicine, Gunma University Hospital, Gunma, Japan.
  • Okamoto S; Hematology Division, Department of Medicine, Keio University Hospital, Tokyo, Japan.
  • Gadbaw B; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
  • Yamauchi K; Novartis Pharma KK, Tokyo, Japan.
  • Amagasaki T; Novartis Pharma KK, Tokyo, Japan.
  • Ito K; Novartis Pharma KK, Tokyo, Japan.
  • Hino M; Department of Hematology, Osaka City University Hospital, Osaka, Japan.
Int J Hematol ; 107(2): 173-184, 2018 Feb.
Article in En | MEDLINE | ID: mdl-28956263
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycythemia Vera / Pyrazoles / Splenomegaly / Janus Kinase Inhibitors / Hydroxyurea Type of study: Clinical_trials / Etiology_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Int J Hematol Journal subject: HEMATOLOGIA Year: 2018 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycythemia Vera / Pyrazoles / Splenomegaly / Janus Kinase Inhibitors / Hydroxyurea Type of study: Clinical_trials / Etiology_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Int J Hematol Journal subject: HEMATOLOGIA Year: 2018 Type: Article Affiliation country: Japan