[A rare endolaryngeal tumor]. / Une tumeur rare endolaryngée.
Ann Pathol
; 37(5): 420-424, 2017 Oct.
Article
in Fr
| MEDLINE
| ID: mdl-28964599
We report the case of a 65-year-old woman who presented with a dysphonia. ENT tomography and laryngoscopy showed an endolaryngeal tumoral lesion extended to the right supraglottis. Biopsy of the lesion revealed dense lymphoid infiltrate in the lamina propria, without necrosis or ulceration of the mucosa. The infiltrate showed many CD3+, CD5+, CD4+, CD8+ lymphocytes and plasmocytes. Larger lymphoid cells with cytologic atypia expressed CD56 and cytotoxicity markers such as TIA1 and granzyme B. In situ hybridization for EBV revealed numerous positive cells. The diagnosis of extranodal NK/T cell lymphoma was proposed. The primary laryngeal localization of this disease is exceptionally rare. Heavy admixture of inflammatory cells may mimic inflammatory process and delay the diagnosis.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Laryngeal Neoplasms
/
Lymphoma, Extranodal NK-T-Cell
Type of study:
Etiology_studies
Limits:
Aged
/
Female
/
Humans
Language:
Fr
Journal:
Ann Pathol
Year:
2017
Type:
Article