Thiadiazolidinone-8 Ameliorates Inflammation Associated with Experimental Colitis in Mice.

Mateus, Vanessa; Rocha, João; Alves, Paula; Mota-Filipe, Hélder; Sepodes, Bruno; Pinto, Rui

Mateus, Vanessa; Rocha, João; Alves, Paula; Mota-Filipe, Hélder; Sepodes, Bruno; Pinto, Rui.

Affiliation

Mateus V; Escola Superior de Tecnologia da Saúde de Lisboa (ESTeSL), Instituto Politécnico de Lisboa, Lisboa, Portugal.

Pharmacology ; 101(1-2): 35-42, 2018.

Article in En | MEDLINE | ID: mdl-28965119

Subject(s)

Anti-Inflammatory Agents/therapeutic use; Colitis/drug therapy; Thiadiazoles/therapeutic use; Alanine Transaminase/blood; Animals; Anti-Inflammatory Agents/pharmacology; Colitis/chemically induced; Colitis/immunology; Colon/drug effects; Colon/immunology; Colon/pathology; Cytokines/immunology; Glycogen Synthase Kinase 3 beta/antagonists & inhibitors; Male; Mice; Peroxidase/immunology; Thiadiazoles/pharmacology; Trinitrobenzenesulfonic Acid

Key words

Experimental colitis; Glycogen synthase kinase-3ß inhibitor; Inflammation; Inflammatory bowel disease; Thiadiazolidinone-8; Trinitrobenzene sulfonic acid-induced colitis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiadiazoles / Colitis / Anti-Inflammatory Agents Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Pharmacology Year: 2018 Type: Article Affiliation country: Portugal

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