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Circulating tumor cells in urological cancers.
Cegan, Martin; Kobierzycki, Christopher; Kolostova, Katarina; Kiss, Imrich; Bobek, Vladimir; Grill, Robert.
Affiliation
  • Bobek V; Department of Laboratory Genetics, University Hospital Kralovske Vinohrady, Prague, Czech Republic; Department of Histology and Embryology, Wroclaw Medical University, Wroclaw, Poland; 3rd Department of Surgery, Motol University Hospital and 1st Faculty of Medicine, Charles University, Prague, Czech Republic. vbobek@centrum.cz.
Folia Histochem Cytobiol ; 55(3): 107-113, 2017.
Article in En | MEDLINE | ID: mdl-28994093
Circulating tumor cells (CTC) represent a very small subpopulation of the cancer cells found in the bloodstream of patients in the metastatic phase of neoplastic disease. Due to the timeline of the disease, they are regarded as a negative prognostic marker. This study focused on determining CTC percentages; these values vary be-tween different types of cancer. In addition to their diagnostic use, CTCs may also be used to treat the disease. Calculating CTC population size and analyzing their biology in patients in advanced stages of cancer may prove valuable in creating a molecular profile for the disease. This would strongly encourage diagnostics and enable personalized treatment. We here present an analysis of recent data on CTCs in urological cancers and their potential uses.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urologic Neoplasms / Neoplastic Cells, Circulating Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Journal: Folia Histochem Cytobiol Journal subject: HISTOCITOQUIMICA Year: 2017 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urologic Neoplasms / Neoplastic Cells, Circulating Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Journal: Folia Histochem Cytobiol Journal subject: HISTOCITOQUIMICA Year: 2017 Type: Article