Distinct roles of intracellular heat shock protein 70 in maintaining gastrointestinal homeostasis.

Wang, Yunwei; Lin, Fanfei; Zhu, Xiaorong; Leone, Vanessa A; Dalal, Sushila; Tao, Yun; Messer, Jeannette S; Chang, Eugene B

Wang, Yunwei; Lin, Fanfei; Zhu, Xiaorong; Leone, Vanessa A; Dalal, Sushila; Tao, Yun; Messer, Jeannette S; Chang, Eugene B.

Affiliation

Wang Y; Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago , Chicago, Illinois.
Lin F; Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago , Chicago, Illinois.
Zhu X; Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago , Chicago, Illinois.
Leone VA; Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago , Chicago, Illinois.
Dalal S; Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago , Chicago, Illinois.
Tao Y; Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago , Chicago, Illinois.
Messer JS; Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago , Chicago, Illinois.
Chang EB; Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago , Chicago, Illinois.

Am J Physiol Gastrointest Liver Physiol ; 314(2): G164-G178, 2018 02 01.

Article in En | MEDLINE | ID: mdl-29051186

Subject(s)

Colitis/metabolism; Colon/metabolism; HSP70 Heat-Shock Proteins/metabolism; Intestinal Mucosa/metabolism; Adoptive Transfer; Animals; Cells, Cultured; Colitis/chemically induced; Colitis/genetics; Colitis/immunology; Colon/immunology; Colon/pathology; Dextran Sulfate; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases/metabolism; HSP70 Heat-Shock Proteins/deficiency; HSP70 Heat-Shock Proteins/genetics; HSP70 Heat-Shock Proteins/immunology; Homeostasis; Immunity, Mucosal; Interleukin-10/genetics; Interleukin-10/metabolism; Intestinal Mucosa/immunology; Intestinal Mucosa/pathology; Leukocyte Common Antigens/immunology; Leukocyte Common Antigens/metabolism; Male; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Signal Transduction; T-Lymphocytes, Regulatory/immunology; T-Lymphocytes, Regulatory/metabolism; T-Lymphocytes, Regulatory/transplantation; Tight Junctions/immunology; Tight Junctions/metabolism; Trinitrobenzenesulfonic Acid; Zonula Occludens-1 Protein/metabolism

Key words

gastrointestinal homeostasis; heat shock protein; inflammatory bowel diseases

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis / Colon / HSP70 Heat-Shock Proteins / Intestinal Mucosa Type of study: Prognostic_studies Language: En Journal: Am J Physiol Gastrointest Liver Physiol Journal subject: FISIOLOGIA / GASTROENTEROLOGIA Year: 2018 Type: Article

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